In European bitcoin casinos regularly hold tournaments, the election of the best players. The prizes there are often large sums of money. Some of the tournaments allow not only to complicate the game, but also to get real money, you can read more here https://www.mensjournal.com/entertainment/best-crypto-betting-sites/. So virtual gamblers should not despair - for relatively little money they can experience quite real money losses. It remains only to understand how to behave in such tournaments and where to play so as not to lose money. Or do you want to lose money? Ahem.