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I have tried Dominion 2L and was not impressed with it. It had about 25% of the effect of Admire. I am now using a 16 OZ bottle of something called Flee. It works great but can be expensive if you have a lot of dogs. A 16 ounce bottle will do 8 big dogs. You must spray down the back every 30 days.
3cc on the dog is what I done. I mixed with water in sprayer and sprayed pens. 2 oz to the gallon. I sprayed once a week until they were gone. It took about 4 week's before they was gone for good.