Welcome to the message board forum for Krukenbergs Spindle and Pigment Dispersion Syndrome.
Here you will be able to post messages or reply to messages posted by other people... share your experiences of PDS or Krukenbergs.
Tracy's Message Board Forum
Welcome to the message board forum for Krukenbergs Spindle and Pigment Dispersion Syndrome. Here you will be able to post messages or reply to messages posted by other people... share your experiences of PDS or Krukenbergs. |
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| Author | Comment |
Julie
 IP: 164.116.74.102 Nov 21, 07 - 5:22 PM |
Iritis
Hi Everyone, I am wondering if anyone has had any auto-immune disorders associated with their PDS? When I have a "flare-up" of iritis and the pigment starts floating around I have severe eye pain and headaches. I also have a B12 deficiency that has yet to be explained (on my 3rd dr.) and diagnosed with Irritable Bowel Syndrome that doesn't really act like everyone else's IBS so I doubt that is a correct diagnosis. I have been reading about auto-immune diseases that can cause iritis which I think is the official name for my flare-ups. Are they connected to PDS? I am concerned that I have too many dr.s who don't have a big picture idea and are not looking at me holistically. Has anyone heard or been to an ocular immunologist? I'm just curious if anyone has experienced anything similar. I am very grateful for this website and the people who respond. It is very comforting! Thanks again, Julie 
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Dave
IP: 193.62.251.16 Nov 22nd, 2007 - 11:38 AM |
Re: Iritis
Pigment Dispersion Syndrome has never really been associated with auto-immune disorders. There have been conflicting reports regarding Human Leukocyte Antigen but this has never been substantiated. HLA, as you probably know, has been linked with many auto-immune disorders and recurrent iritis. It has been known for recurrent iritis to be mistaken for PDS as inflammation involving the posterior surface of the iris can occasionally disperse a moderate amount of pigment often clumped in the inferior angle. Intra-Ocular Pressure can also be raised (and lowered) in anterior uveitis. However, other signs of inflammation are usually present. It has been noted that patients with PDS seem to exhibit a greater respond to epinephrine compounds than any other glaucoma. Adrenergic hypersensitivity might explain this phenomenon, which has never been formally or prospectively examined. Patients with PDS/PG also seem more prone than average to cardiovascular disease, compatible with generalized adrenergic hypersensitivity. There are many ophthalmologists interested in auto-immune disorders & ocular inflammation, mostly in response to their effect on anterior surface function & dry eye. Certainly most NHS trusts in the U.K. would have a service available. I don't believe it would be too difficult to find one in the U.S. Please post again if I have been unclear. Dave |
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